Course title: CHEMISTRY
Semester: 1 / Winter
Lectures/Classes: 15 / 30 hours
Field of study: Veterinary Medicine
Study cycle: 1st cycle
Type of course: compulsory
Contact person:
Short description: The aim of the course is to familiarize students with general chemistry (with special emphasis on chemical processes in aqueous solutions), with quantitative and qualitative analysis, as well as with calculations (ionic equilibrium, buffers). Students will be familiarized with general principles of organic chemistry (atomic and molecular orbitals, nucleophilic substitution, elimination, and addition reaction, free radical reaction), structure and chemical properties of organic compounds with one functional group, carbohydrates, lipids, amines, aminoacids, peptide bond, nucleotides.
Full description: General principles of solutions - true solutions and colloids, colligative properties, osmotic pressure and its biological significance. Iionic equilibrium in aqueous solution - the dissociation of ionic electrolytes, degree of dissociation, dissociation constant, pH, buffered solutions and their biological significance. Basal principles of chemical reactions kinetics. General principles of organic chemistry – atomic and molecular orbitals, hybridization and the nature of the chemical bonds, nomenclature and conformation of alkanes, van der Waals forces, chemical properties of alkanes, cycloalkanes, aromatic alkanes, stereoisomers, nucleophilic substitution reaction, elimination reaction, addition reaction. Organic compounds with one functional group (structure and chemical properties) – alcohols, phenols, compounds with carbonyl group: aldehydes, ketones, esters; mechanism of nucleophilic addition to carbonyl group; carboxylic acides and their derivates. Structure and chemical properties of carbohydrates. Biologically significant carbohydrate derivates (glycosides). Structure and chemical properties of lipids (triglycerides, fatty acids, complex lipids, cholesterol and its derivates). Structure and chemical properties of amines, and azo compunds. Biologically active amines (sulfa drugs, alkaloids, catecholamines). Principles of amino acids, peptide bond formation, proteins. Structure of nucleotides and nucleic acids. Structure of heterocyclic compounds with one or more heteroatoms (N, O, S). Qualitative analysis. Chemical calculations (degree of dissociation, dissociation constant, buffers). Quantitative analysis – titration (argentometry, redox titration, complexometric titration). Spectrophotometry – basic concepts (theoretical and practical).
Bibliography: 1. Basic manual: Timberlake K.C. 2014 (or later edition). General, Organic, and Biological Chemistry. Pearson International Edition. 2. Supplementary manual (in a library reading room): Solomons T.W.G. Fryhle C.B.2007 (or later edition). Organic Chemistry. John Wiley & Sons, Inc.
Learning outcomes: Knowledge: - describe basal chemical processes concerning ionic equilibrium in aqueous solutions, define basal principles of colligative properties of solutions - explain the principles of buffer solutions and their importance for living organisms, define and presents basal principles of chemical reactions kinetic - classify and describe basal chemical properties of organic compounds with one or two functional groups - recognize structures and names of chemical compounds, especially basic building blocks of living organisms and biologically active compounds Skills: - use the common laboratory equipment - perform basic chemical qualitative and quantitative determinations - perform calculations concerning concentrations, pH, buffering properties, rate of chemical reactions, chemical equilibrium Social competences: - student is able to use the basic laboratory equipment, lead basic chemical examinations and calculations - student obtains the knowledge necessary for biochemistry, pharmacology and toxicology course
Assessment methods and assessment criteria: Final assessment: 50% rating from classes + 50% an assessment of credit from the lectures (exam).

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